Damage to the brain may begin as many as 10 to 20 years before any problems are evident. Memory problems are often the first signs of the disease. Some people develop a condition known as mild cognitive impairment (MCI). They have more memory problems than normal for their age, but their symptoms are not as severe as in Alzheimer’s. Individuals with MCI are at increased risk for developing Alzheimer’s disease. Most people with Alzheimer’s disease have “late onset” Alzheimer’s, which usually develops after age 60. In rare cases, people develop “early onset” Alzheimer’s in their 30’s, 40’s and 50’s due to a genetic mutation.